274194

Methyl 3,4,5-trihydroxybenzoate

98%

• Synonyme(s) : Methyl gallate
• Formule linéaire : (HO)₃C₆H₂CO₂CH₃
• CAS Number: 99-24-1
• Poids moléculaire : 184.15
• Beilstein: 2113180
• Numéro CE : 202-741-7
• Numéro MDL: MFCD00002194
• Code UNSPSC : 12162002
• ID de substance PubChem : 24856570
• Nomenclature NACRES : NA.23

Propriétés

• Essai: 98%
• Pf: 201-203 °C (lit.)
• Chaîne SMILES: COC(=O)c1cc(O)c(O)c(O)c1
• InChI: 1S/C8H8O5/c1-13-8(12)4-2-5(9)7(11)6(10)3-4/h2-3,9-11H,1H3
• Clé InChI: FBSFWRHWHYMIOG-UHFFFAOYSA-N

Description

Description générale

Methyl 3,4,5-trihydroxybenzoate, also known as methyl gallate, is a derivative of gallic acid with three hydroxyl groups and an ester linkage, which contributes to its reactivity and solubility in organic solvents. It exhibits strong free radical scavenging activity, which is crucial in preventing oxidative stress in biological systems and enhancing the lifespan of materials. Its natural origin and low toxicity make it suitable for biomedical applications, particularly in drug delivery and tissue engineering.

Application

Methyl 3,4,5-trihydroxybenzoate can be used:

• As a precursor to synthesize nanocomposite drug delivery systems for lung cancer treatment. It has low toxicity and can induce apoptosis by generating free radicals.
• As a starting material to prepare norbornene-based main-chain polymers via ring-opening metathesis polymerization (ROMP), for biomedical uses to coatings and electronics.
• As an additive in the pretreatment of Sugarcane Bagasse for the removal of lignin from biomass and consequently the cellulose hydrolysis. This process helps the use of biomass as energy currency for various biotechnological processes

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302,H315,H319,H335
• Conseils de prudence: P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Faceshields, Gloves