27885

Coumestrol

≥95.0% (HPLC)

• Synonyme(s) : 7,12-Dihydroxycoumestan
• Formule empirique (notation de Hill) : C₁₅H₈O₅
• CAS Number: 479-13-0
• Poids moléculaire : 268.22
• Beilstein: 266702
• Numéro CE : 207-525-6
• Numéro MDL: MFCD00016885
• Code UNSPSC : 41116107
• ID de substance PubChem : 57648279
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Essai: ≥95.0% (HPLC)
• Forme: powder
• Impuretés: ≤10.0% water
• Pf: ≥350 °C (lit.)
• Chaîne SMILES: Oc1ccc-2c(OC(=O)c3c-2oc4cc(O)ccc34)c1
• InChI: 1S/C15H8O5/c16-7-1-3-9-11(5-7)19-14-10-4-2-8(17)6-12(10)20-15(18)13(9)14/h1-6,16-17H
• Clé InChI: ZZIALNLLNHEQPJ-UHFFFAOYSA-N
• Informations sur le gène: human ... ESR1(2099), ESR2(2100) ; mouse ... Esr1(13982) ; rat ... Ar(24208)

Description

Application

• Phytoestrogens in Fish Feed Production:Coumestrolis is used as a biomarkers in fish feed production, facilitating the assessment of plant raw materials used in these feeds (Pavlopoulos et al., 2023).


• Coumestrol and Soybean Leaf Senescence: Coumestrol′s role in soybean leaf senescence is explored, particularly its interactions with phytohormones, suggesting potential agronomic benefits and applications in crop science, it acts as a phytoalexin (Mun et al., 2021).


• Systemic Defense in Soybeans: Investigating the effects of priming with coumestrol on soybean defense against the root-lesion nematode, this research highlights its potential as a natural plant defense enhancer (Adss et al., 2021).

Actions biochimiques/physiologiques

Coumestrol has anti-estrogenic actions in the brain and pituitary, mediated through estrogen receptor-α.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302,H315,H319,H335
• Conseils de prudence: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves