85605

Spermine tetrahydrochloride

BioUltra, Molecular Biology, ≥99.5% (AT)

• Synonyme(s) : N,N′-Bis(3-aminopropyl)-1,4-butanediamine tetrahydrochloride
• Formule empirique (notation de Hill) : C₁₀H₂₆N₄ · 4HCl
• CAS Number: 306-67-2
• Poids moléculaire : 348.18
• Beilstein: 3911771
• Numéro CE : 206-189-8
• Numéro MDL: MFCD00012914
• Code UNSPSC : 12352116
• ID de substance PubChem : 57653056
• Nomenclature NACRES : NA.26

Propriétés

• Qualité: Molecular Biology
• Niveau de qualité: 300
• Gamme de produits: BioUltra
• Essai: ≥99.5% (AT)
• Forme: powder
• Impuretés: DNases, none detected; RNases, none detected; insoluble matter, passes filter test; phosphatases, none detected; proteases, none detected
• pH: 4.5-7.0 (25 °C, 1 M in H₂O)
• Pf: 310-311 °C (dec.) (lit.)
• Solubilité: H₂O: 1 m at 20 °C, clear, colorless to almost colorless
• Traces d'anions: sulfate (SO₄^2-): ≤50 mg/kg
• Traces de cations: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• λ: 1 M in H₂O
• Absorption UV: λ: 260 nm A_max: 0.2; λ: 280 nm A_max: 0.15
• Chaîne SMILES: Cl.Cl.Cl.Cl.NCCCNCCCCNCCCN
• InChI: 1S/C10H26N4.4ClH/c11-5-3-9-13-7-1-2-8-14-10-4-6-12;;;;/h13-14H,1-12H2;4*1H
• Clé InChI: XLDKUDAXZWHPFH-UHFFFAOYSA-N

Description

Application

Used to precipitate DNA from low salt aqueous buffers.

Actions biochimiques/physiologiques

Mixed NMDA agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).

Mixed NMDA agonist/antagonist at the polyamine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).

Mixed NMDA agonist/antagonist at the polyamine site. Role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).

Autres remarques

Spermine precipitation of DNA.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319
• Conseils de prudence: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2
• Code de la classe de stockage: 13 - Non Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves