A7236

Anacardic acid

• Synonyme(s) : 2-Hydroxy-6-pentadecylbenzoic acid, 22:0-Anacardic acid, 6-Pentadecylsalicylic acid
• Formule empirique (notation de Hill) : C₂₂H₃₆O₃
• CAS Number: 16611-84-0
• Poids moléculaire : 348.52
• Numéro MDL: MFCD07368254
• Code UNSPSC : 12352106
• ID de substance PubChem : 329770923
• Nomenclature NACRES : NA.77

Propriétés

• Forme: powder
• Niveau de qualité: 100
• Conditions de stockage: protect from light
• Couleur: white to beige
• Solubilité: DMSO: ≥20 mg/mL
• Température de stockage: −20°C
• Chaîne SMILES: CCCCCCCCCCCCCCCc1cccc(O)c1C(O)=O
• InChI: 1S/C22H36O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19-17-15-18-20(23)21(19)22(24)25/h15,17-18,23H,2-14,16H2,1H3,(H,24,25)
• Clé InChI: ADFWQBGTDJIESE-UHFFFAOYSA-N

Description

Application

Anacardic acid has been used:

• as a histone acetylase (HAT) inhibitor to study its effects on rat cortical neurons
• as a positive control in acetylation assay in vitro
• as an acetylase inhibitor to study its effects on the ribonucleic acid export 1 (Rae-1) protein acetylation that was transfected in human embryonic kidney cells

Actions biochimiques/physiologiques

Anacardic acid is a HAT (Histone Acetyltransferase) inhibitor.

Anacardic acid is a natural bioactive compound derived from the nutshell of Anacardium occidentale. It possesses anti-fungal, anti-bacterial, anti-termite, and molluscicidales activities. Anacardic acid acts as a therapeutic agent against obesity, cancer, inflammatory disorders, and oxidative damage. It functions as an inhibitor of various enzymes such as lipoxygenase (LOX-1), xanthine oxidase, nuclear factor κ B (NFκB) kinase, tyrosinase, and ureases.

Caractéristiques et avantages

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Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable