C8221

Caffeic acid phenethyl ester

≥97% (HPLC), powder

• Synonyme(s) : CAPE
• Formule empirique (notation de Hill) : C₁₇H₁₆O₄
• CAS Number: 104594-70-9
• Poids moléculaire : 284.31
• Numéro MDL: MFCD00866470
• Code UNSPSC : 12352108
• ID de substance PubChem : 24278341
• Nomenclature NACRES : NA.77

Propriétés

• Source biologique: synthetic
• Niveau de qualité: 200
• Essai: ≥97% (HPLC)
• Forme: powder
• Conditions de stockage: protect from light
• Couleur: off-white
• Solubilité: ethyl acetate: 50 mg/mL; DMSO: soluble; ethanol: soluble
• Température de stockage: −20°C
• Chaîne SMILES: Oc1ccc(\C=C\C(=O)OCCc2ccccc2)cc1O
• InChI: 1S/C17H16O4/c18-15-8-6-14(12-16(15)19)7-9-17(20)21-11-10-13-4-2-1-3-5-13/h1-9,12,18-19H,10-11H2/b9-7+
• Clé InChI: SWUARLUWKZWEBQ-VQHVLOKHSA-N
• Informations sur le gène: human ... NFKB2(4791)

Description

Application

Caffeic acid phenethyl ester (CAPE) has been used to determine the effect of CAPE in hyperthyroidism, as a component of culture media to measure the cytotoxicity of breast cancer cell line MDA-MB-231, to study its effects on amiodarone-induced pulmonary fibrosis in rats.

Actions biochimiques/physiologiques

CAPE exhibits several properties such as anticarcinogenic, immunomodulatory activities, antioxidant, antiviral, anti-inflammatory, hypoglycaemic effect, cardioprotective and inhibits gastric secretion. It also has an inhibitory effect on fibroblasts growth factor type 2 (FGF-2), a tumor growth factor in breast cancer.

Caffeic acid phenethyl ester is a specific inhibitor of the nuclear transcription factor NF-κB.

Caractéristiques et avantages

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Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves