G9003

D-Glutamine

≥98% (HPLC)

• Synonyme(s) : D-2-Aminoglutaramic acid, D-Glutamic acid 5-amide
• Formule empirique (notation de Hill) : C₅H₁₀N₂O₃
• CAS Number: 5959-95-5
• Poids moléculaire : 146.14
• Beilstein: 1723796
• Numéro MDL: MFCD00065607
• Code UNSPSC : 12352209
• ID de substance PubChem : 24895357
• Nomenclature NACRES : NA.32

Propriétés

• Product Name: D-Glutamine, ≥98% (HPLC)
• Niveau de qualité: 100
• Essai: ≥98% (HPLC)
• Forme: powder
• Couleur: white
• Application(s): cell analysis
• Chaîne SMILES: N[C@H](CCC(N)=O)C(O)=O
• InChI: 1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m1/s1
• Clé InChI: ZDXPYRJPNDTMRX-GSVOUGTGSA-N

Description

Description générale

Glutamine is a non-essential and the most abundant free amino acid present in the human body. It is an important component of proteins and is one of the 20 proteinogenic amino acids. It forms 5-6% of bound amino acids.

Application

D-Glutamine has been used to study its role in conferring protection against acetaldehyde-induced disruption of barrier function in Caco-2 cell monolayer.

Actions biochimiques/physiologiques

Glutamine forms the central metabolite in amino acid transamination via a-ketoglutarate and glutamic acid. This amino acid is metabolized by different enzymes, such as glutaminase, present in liver, and glutamine synthetase, present in skeletal muscle. It is produced in the cytoplasm from other amino acids, predominantly from branched-chain amino acids and glutamate. It plays an essential role in ammonia metabolism and detoxification. Its skeletal muscle levels are significantly reduced post trauma, operation and inflammatory states. It servers as a prognostic marker in fatal sepsis during which its skeletal muscle levels are decreased by 90%.

Autres remarques

Unnatural isomer of glutamine

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)