I1896

Interleukin-13 from mouse

≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

• Synonyme(s) : IL-13
• Numéro MDL: MFCD00675503
• Code UNSPSC : 12352202
• Nomenclature NACRES : NA.32

Propriétés

• Source biologique: mouse
• Niveau de qualité: 100
• Produit recombinant: expressed in E. coli
• Essai: ≥97% (SDS-PAGE)
• Forme: lyophilized powder
• Puissance: 1-10 ng/mL EC₅₀
• Poids mol.: 11.5 kDa (predicted; 9 kDa under reducing conditions)
• Conditionnement: pkg of 5 μg
• Technique(s): cell culture | mammalian: suitable
• Impuretés: endotoxin, tested
• Numéro d'accès UniProt: P20109
• Température de stockage: −20°C
• Informations sur le gène: mouse ... Il13(16163)

Description

Actions biochimiques/physiologiques

Interleukin-13 is a pleiotropic cytokine produced by activated Th2 cells in the mouse and human. IL-13 is secreted mainly as an unglycosylated protein of 132 amino acids with a molecular weight of 10,000 daltons. A 4.3kb DNA fragment of the mouse IL-13 gene was sequenced and occurs as a single copy mapping a chromosome 11. In the human, a 4.6 kb DNA segment of the IL-13 gene occurs as a single copy and maps to chromosome 5. IL-13 induces B cell proliferation and also induces IgE switching. The proliferative activity of human and mouse IL-13 products are tested in culture using the human erythroleukemic cell line TF-1.

Forme physique

lyophilized from a 0.2 μm filtered solution in phosphate buffered saline (PBS), pH 7.4, with 50 μg bovine serum albumin (BSA) per 1 μg of cytokine

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves