I4777

Interferon-γ from mouse

≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

• Synonyme(s) : IFN-γ
• Numéro MDL: MFCD00131391
• Code UNSPSC : 12352202
• Nomenclature NACRES : NA.32

Propriétés

• Source biologique: mouse
• Niveau de qualité: 200
• Produit recombinant: expressed in E. coli
• Essai: ≥98% (SDS-PAGE)
• Forme: lyophilized powder
• Poids mol.: protein 15.6 kDa
• Conditionnement: pkg of 0.1 mg
• Technique(s): cell culture | mammalian: suitable
• Impuretés: endotoxin, tested
• Couleur: white
• Solubilité: water: soluble 1.000 mL, clear, colorless
• Numéro d'accès UniProt: P01580
• Température de stockage: −20°C
• Informations sur le gène: mouse ... Ifng(15978)

Description

Application

Interferon-γ from mouse has been used:

• for in vitro stimulation of the BMDC (bone marrow derived dendritic cell), BMM (bone marrow-derived macrophages) and CD11c⁺ (CD11 antigen-like family member C) lung macrophages
• for stimulation of murine macrophages to induce the production of nitrite and nitrate
• to check CCAAT/enhancer binding protein β (C/EBPβ)-mediated changes in the expression of prostaglandin synthesis enzymes in neuroinflammation

Actions biochimiques/physiologiques

Ifng (interferon-γ) plays an important role in innate and adaptive immune responses, and helps in defense against bacterial infections, dimorphic yeast and some viral infections.

Forme physique

Lyophilized from a 0.2 μm filtered buffered solution. Package size based on protein content.

Remarque sur l'analyse

The biological activity of recombinant mouse IFN-γ is measured by its ability to inhibit the proliferation of murine WEHI-279 cells.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)