O9139

N-(3-Oxododecanoyl)-L-homoserine lactone

≥98% (TLC)

• Synonyme(s) : 3-Oxo-C₁₂-HSL
• Formule empirique (notation de Hill) : C₁₆H₂₇NO₄
• CAS Number: 168982-69-2
• Poids moléculaire : 297.39
• Numéro MDL: MFCD08275140
• Code UNSPSC : 12352209
• eCl@ss : 32160406
• ID de substance PubChem : 329818935
• Nomenclature NACRES : NA.26

Propriétés

• Product Name: N-(3-Oxododecanoyl)-L-homoserine lactone, quorum sensing signaling molecule
• Niveau de qualité: 200
• Essai: ≥98% (TLC)
• Forme: powder
• Couleur: white
• Application(s): cell analysis
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Chaîne SMILES: CCCCCCCCCC(=O)CC(=O)N[C@H]1CCOC1=O
• InChI: 1S/C16H27NO4/c1-2-3-4-5-6-7-8-9-13(18)12-15(19)17-14-10-11-21-16(14)20/h14H,2-12H2,1H3,(H,17,19)/t14-/m0/s1
• Clé InChI: PHSRRHGYXQCRPU-AWEZNQCLSA-N

Description

Application

N-(3-Oxododecanoyl)-L-homoserine lactone (3-Oxo-C12-HSL), a member of a family of acyl homoserine lactones, may be used to determine its mechanisms and specificity of action as a signaling molecule involved in the regulation of bacterial quorum sensing.

Actions biochimiques/physiologiques

N-(3-oxododecanoyl)homoserine-L-lactone (3-oxo-C12-HSL) is among a group of homoserine lactones that includes: N-octanoyl-homoserine lactone (N-C8-HSL), N-(3-oxodecanoyl) homoserine-L-lactone (3-oxo-C10 HSL), N-(3-Oxotetradecanoyl)-L-homoserine lactone (3-oxo-C14-HSL, N-(3-hydroxydecanoyl)-L-homoserine lactone, and N-(3-hydroxyoctanoyl)-L-homoserine lactone involved in the processes of bacterial quorum sensing. These N-acyl-homoserine lactones are used to study the processes and mechanisms of bacterial quorum sensing.

Acyl homoserine lactone that is an autoinducer of quorum sensing by Pseudomonas aeruginosa. Degraded by paraoxonase (PON) family members.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302
• Conseils de prudence: P264 - P270 - P301 + P312 - P501
• Classification des risques: Acute Tox. 4 Oral
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves