860678P

C24 Ceramide-d7 (d18:1-d7/24:0)

Avanti Research^™ - A Croda Brand 860678P, powder

• Synonym(s): N-lignoceroyl-D-erythro-sphingosine (d7)
• Empirical Formula (Hill Notation): C₄₂H₇₆D₇NO₃
• CAS Number: 1840942-15-5
• Molecular Weight: 657.16
• MDL number: MFCD00133433
• UNSPSC Code: 12352100
• NACRES: NA.25

Properties

• form: powder
• packaging: pkg of 1 × 1 mg (860678P-1mg); pkg of 1 × 5 mg (860678P-5mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 860678P
• shipped in: dry ice
• storage temp.: −20°C

Description

General description

C24 Ceramide (d18:1/24:0) is a synthetic ceramide containing sphingosine with lignoceric acid. Ceramide synthase 2 is responsible for the synthesis of C24 ceramide. C24 Ceramide-d7 (d18:1-d7/24:0) is a deuterated derivative of C24 Ceramide (d18:1/24:0).

Application

C24 Ceramide-d7 (d18:1-d7/24:0) has been used as a standard in liquid chromatography–mass spectrometry (LC-MS) for quantitative analysis of C24 ceramide in skeletal muscle.

Biochem/physiol Actions

C24 Ceramide plays a vital role in inducing cell death. Altered levels of C24 ceramide might be a potential indication in tumor monitoring. Determining the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios in human plasma helps to predict fatal outcome of coronary artery disease. The stable isotope form of C24 Ceramide (d18:1/24:0) is convenient for a newly described validated liquid chromatography-tandem mass spectrometry methodology for their clinical-scaled measurement.

Packaging

5 mL Amber Glass Screw Cap Vial (860678P-1mg)

5 mL Amber Glass Screw Cap Vial (860678P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): No data available
• Flash Point(C): No data available