860679P

C24:1 Ceramide-d7 (d18:1-d7/24:1(15Z))

Avanti Research^™ - A Croda Brand 860679P, powder

• Synonym(s): N-nervonoyl-D-erythro-sphingosine (d7)
• Empirical Formula (Hill Notation): C₄₂H₇₄D₇NO₃
• CAS Number: 1840942-16-6
• Molecular Weight: 655.14
• MDL number: MFCD35061399
• UNSPSC Code: 12352100
• NACRES: NA.25

Properties

• form: powder
• packaging: pkg of 1 × 1 mg (860679P-1mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 860679P
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: OC[C@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)[C@@](O)([H])/C=C/CCCCCCCCCCC(C(C([2H])([2H])[2H])([2H])[2H])([2H])[2H]
• InChI key: VJSBNBBOSZJDKB-PVDQZAGSSA-N

Description

General description

C24:1 Ceramide (d18:1/24:1) is a synthetic ceramide derived from sphingosine with nervonic acid (a monounsaturated analog of lignoceric acid (24:0)). C24:1 Ceramide-d7 (d18:1-d7/24:1(15Z)) is a deuterated derivative of C24:1 Ceramide (d18:1/24:1).

Application

C24:1 Ceramide-d7 (d18:1-d7/24:1(15Z)) has been used as a standard in liquid chromatography–mass spectrometry (LC-MS) for quantitative analysis of C24:1 ceramide in skeletal muscle. It has also been used as a standard to measure C40-C44 ceramides in zebrafish brain and human embryonic kidney cell line (HEK293) by thermo q-exactive plus quadrupole-orbitrap mass spectrometery.

Biochem/physiol Actions

Monitoring the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios in human plasma aids the prognosis of fatal outcome of coronary artery disease. C24:1 Ceramide (d18:1/24:1) in a stable isotope form is suitable for a newly described validated liquid chromatography-tandem mass spectrometry methodology for their clinical-scaled measurement.

Packaging

5 mL Amber Glass Screw Cap Vial (860679P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• Flash Point(F): No data available
• Flash Point(C): No data available