M4758

(±)-6-Methyl-5,6,7,8-tetrahydropterine dihydrochloride

~95% (TLC)

• Synonym(s): 6-MPH₄, DL-2-Amino-4-hydroxy-6-methyl-5,6,7,8-tetrahydropteridine dihydrochloride
• Empirical Formula (Hill Notation): C₇H₁₁N₅O · 2HCl
• CAS Number: 69113-63-9
• Molecular Weight: 254.12
• Beilstein: 5648114
• MDL number: MFCD00058175
• UNSPSC Code: 12352204
• PubChem Substance ID: 24896941
• NACRES: NA.51

Properties

• Assay: ~95% (TLC)
• Quality Level: 200
• storage temp.: −20°C
• SMILES string: Cl.Cl.CC1CNc2nc(N)nc(O)c2N1
• InChI: 1S/C7H11N5O.2ClH/c1-3-2-9-5-4(10-3)6(13)12-7(8)11-5;;/h3,10H,2H2,1H3,(H4,8,9,11,12,13);2*1H
• InChI key: MKQLORLCFAZASZ-UHFFFAOYSA-N

Description

Application

6-MPH4 is used to study mechanisms of nitric oxide (NO) synthase and free radical induced L-DOPA release from striatal tissue.

Biochem/physiol Actions

Synthetic cofactor for tyrosine hydrolase; also cofactor for phenylalanine and tryptophan hydroxylases; less activity than the natural cofactor, BH₄

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves