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Key Documents

U9507

Sigma-Aldrich

Urocortin II mouse

Synonym(s):

UCN-II

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.32

biological source

mouse

Quality Level

Assay

≥97% (HPLC)

form

solid

technique(s)

immunohistochemistry: suitable

UniProt accession no.

storage temp.

−20°C

Gene Information

mouse ... Ucn2(171530)

Amino Acid Sequence

Val-Ile-Leu-Ser-Leu-Asp-Val-Pro-Ile-Gly-Leu-Leu-Arg-Ile-Leu-Leu-Glu-Gln-Ala-Arg-Tyr-Lys-Ala-Ala-Arg-Asn-Gln-Ala-Ala-Thr-Asn-Ala-Gln-Ile-Leu-Ala-His-Val-NH2

Application

Mouse urocortin II can be used for immunohistochemistry.

Biochem/physiol Actions

Urocortin II is a CRF-related neuropeptide having high affinity for CRF2 receptor. It stimulates protein kinase A through CRF2 receptor and increases the contractility in rabbit ventricular myocytes. It also facilitates pro-inflammatory effects in human intestinal cells through corticotropin-releasing hormone receptor 2α.
corticotropin-releasing factor (CRF) peptide

Other Notes

Lyophilized from 0.1% TFA in H2O

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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