764779

Poly(ethylene glycol) methyl ether-block-poly(D,L lactide)

PEG average M_n 2,000, PDLLA average M_n 2,000

• 동의어(들): PEG-PDLLA
• UNSPSC 코드: 12162002
• NACRES: NA.23

속성

• 설명: n=45, m=28 (typical); typical PEG PDI<1.1; overall PDI<1.4 (THF, PEO)
• Quality Level: 100
• 양식: pellets
• 분자량: PDLLA average M_n 2,000; PEG average M_n 2,000; average M_n 4,000 (total)
• 분해 기간: 2-4 weeks
• 전이 온도: T_g 11 °C (PEG block); T_m 244-248 °C; T_g 88 °C (PDLLA block)
• PDI: ≤1.4
• 저장 온도: 2-8°C

설명

일반 설명

Block copolymer micelles are widely used in drug delivery applications. PEG-PDLLA is a biodegradable polymeric micelle which is used as carriers for hydrophobic drugs like paclitaxel. PEG is the hydrophilic part and PDLLA is the hydrophobic part which forms the micelle core wherein the hydrophobic drug is loaded.

애플리케이션

Used as a carrier for the controlled and targeted release of anticancer hydrophobic drugs.

water-solubilization of drugs

특징 및 장점

• Good biocompatibility, low immunogenicity and good degradability.
• Properties can be easily modulated by changing the block copolymer segment sizes to suit a particular application.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable