790451

TCO-amine HCl salt

• 동의어(들): trans-Cyclooctene-amine hydrochloride salt, TCO-NH2, HCl salt
• 실험식(Hill 표기법): C₁₂H₂₂N₂O₂ · HCl
• Molecular Weight: 262.78
• MDL number: MFCD31692192
• UNSPSC 코드: 12352116
• PubChem Substance ID: 329768216
• NACRES: NA.22

속성

• 양식: solid
• Quality Level: 100
• 반응 적합성: reaction type: click chemistry; reagent type: linker
• 작용기: amine
• 저장 온도: −20°C
• SMILES string: O=C(NCCCN)OC1CCC/C=C/CC1.[H]Cl
• InChI: 1S/C12H22N2O2.ClH/c13-9-6-10-14-12(15)16-11-7-4-2-1-3-5-8-11;/h1-2,11H,3-10,13H2,(H,14,15);1H/b2-1+;
• InChI key: GIYQQURLGCGUKK-TYYBGVCCSA-N

설명

애플리케이션

Amine functionalized trans-cyclooctene derivative for incorporation of the cyclooctene moiety into carboxyl containing compounds or biomolecules via standard coupling techniques (DCC; EDC etc...). Trans-cyclooctenes are useful in strain-promoted copper-free click chemistry cycloaddition reactions with 1; 2; 4; 5-tetrazines. This cyclooctene will react with tetrazine functionalized compounds or biomolecules without the need for a catalyst to result in a stable covalent linkage. The 4+2 inverse electron demand Diels-Alder cycloaddition between trans-cyclooctene and tetrazines is the fastest biologically compatible ligation technology reported and has had many applications in biological labeling and imaging.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable