700052P

22(R)-hydroxycholesterol-d7

Avanti Research^™ - A Croda Brand

• 동의어(들): 25,26,26,26,27,27,27-heptadeuterocholest-5-ene-3β,22R-diol
• 실험식(Hill 표기법): C₂₇H₃₉O₂D₇
• CAS Number: 1246302-93-1
• Molecular Weight: 409.70
• MDL number: MFCD00272990
• UNSPSC 코드: 41141804
• NACRES: NA.25

속성

• 설명: cholest-5-ene-3β,22(R)-diol-d7
• 분석: >99% (TLC)
• 양식: powder
• 포장: pkg of 1 × 1 mg (700052P-1mg)
• 제조업체/상표: Avanti Research^™ - A Croda Brand
• 응용 분야: lipidomics; metabolomics
• 배송 상태: dry ice
• 저장 온도: −20°C

설명

일반 설명

22(R)-hydroxycholesterol is a diastereomer of 22(S)-hydroxycholesterol. It is present in the neonate brain. 22(R)-hydroxycholesterol-d7 is a deuterated form of 22(R)-hydroxycholesterol.

생화학적/생리학적 작용

22(R)-hydroxycholesterol (22(R)-HC) is a liver X receptor (LXR) ligand and is a key for the receptor activation.. 22(R)-HC promotes mesenchymal stem cell osteogenesis along with other oxysterols. It also regulates cholesterol homeostasis and suppresses prostate tumor progression. Low levels of 22(R)-HC is observed in Alzheimer′s disease and may be implicated in neuroinflammation and neurodegenerative diseases.

포장

5 mL Amber Glass Screw Cap Vial (700052P-1mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids