700056P

lathosterol-d7

Avanti Research^™ - A Croda Brand

• 동의어(들): 5α-Cholest-7-en-3β-ol (25,26,26,26,27,27,27-d7)
• 실험식(Hill 표기법): C₂₇H₃₉D₇O
• CAS Number: 2260669-10-9
• Molecular Weight: 393.70
• MDL number: MFCD22416731
• UNSPSC 코드: 41141804
• NACRES: NA.25

속성

• 분석: >99% (TLC)
• 양식: powder
• 포장: pkg of 1 × 1 mg (700056P-1mg)
• 제조업체/상표: Avanti Research^™ - A Croda Brand
• 배송 상태: dry ice
• 저장 온도: −20°C

설명

일반 설명

Lathosterol is a metabolite of cholesterol present in human breast milk. Lathosterol is catabolized by lathosterol 5-desaturase to 7-dehydrocholesterol, which is a precursor of cholesterol. Lathosterol-d7 is a deuterated derivative of lathosterol.

애플리케이션

Lathosterol-d7 has been used as an internal standard in gas chromatography-mass spectrometry (GC–MS) for the breast milk sterol quantification and in liquid chromatography high resolution mass spectrometry (LC–HRMS) analysis.

생화학적/생리학적 작용

Lathosterol levels are direct indicators of cholesterol levels and aid in decoding metabolism defects. Elevated levels of lathosterol is implicated in cerebrotendinous xanthomatosis (CTX) and lathosterolosis. The inactivation of enzyme lathosterol 5-desaturase (SC5D) leads to accumulation of lathosterol in lathosterolosis pathology.

포장

5 mL Amber Glass Screw Cap Vial (700056P-1mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• Flash Point (°F): No data available
• Flash Point (°C): No data available