E2271

Ectoine

osmoprotectant

• 동의어(들): (S)-2-Methyl-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid, Thp(B)
• 실험식(Hill 표기법): C₆H₁₀N₂O₂
• CAS Number: 96702-03-3
• Molecular Weight: 142.16
• Beilstein: 7288977
• EC Number: 431-910-1
• MDL number: MFCD03419286
• UNSPSC 코드: 12352204
• PubChem Substance ID: 24894465
• NACRES: NA.25

속성

• Quality Level: 200
• 분석: ≥98.0% (HPLC); ≥98.0% (TLC)
• 양식: powder
• 분자량: 142.16
• 저장 온도: room temp
• SMILES string: CC1=N[C@@H](CCN1)C(O)=O
• InChI: 1S/C6H10N2O2/c1-4-7-3-2-5(8-4)6(9)10/h5H,2-3H2,1H3,(H,7,8)(H,9,10)/t5-/m0/s1
• InChI key: WQXNXVUDBPYKBA-YFKPBYRVSA-N

설명

일반 설명

Ectoine is a natural cyclic tetrahydropyrimidine, which is a low molecular weight, water-binding and organic osmolyte. It is a part of a class of small molecule chaperones (SMCs).

생화학적/생리학적 작용

Ectoine acts as an osmoprotectant in a wide variety of microorganisms including heterotrophic, halophilic bacteria and non-halophilic bacteria such as Streptomyces species and E.coli. This compatible solute exhibit protective effects in E.coli during drying and storage. Ectoine is implicated in protein and lipid bilayer stabilization. It also regulates the preservation of turgor pressure and ameliorates desiccation stress. It may be used to treat inflammatory diseases such as, allergic rhinitis, atopic dermatitis and chronic obstructive pulmonary disease. Ectoine can cause DNA structural changes in vitro and protects DNA from ionizing radiation (IR). It prevents insulin amyloid formation in vitro.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves