F9677

Felodipine

solid

• 동의어(들): 4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinecarboxylic acid ethyl methyl ester, Plendil
• 실험식(Hill 표기법): C₁₈H₁₉NO₄Cl₂
• CAS Number: 72509-76-3
• Molecular Weight: 384.25
• MDL number: MFCD00868316
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24278449
• NACRES: NA.77

속성

• 양식: solid
• Quality Level: 200
• solubility: DMSO: 20 mg/mL; H₂O: insoluble
• 주관자: AstraZeneca
• SMILES string: CCOC(=O)C1=C(C)NC(C)=C(C1c2cccc(Cl)c2Cl)C(=O)OC
• InChI: 1S/C18H19Cl2NO4/c1-5-25-18(23)14-10(3)21-9(2)13(17(22)24-4)15(14)11-7-6-8-12(19)16(11)20/h6-8,15,21H,5H2,1-4H3
• InChI key: RZTAMFZIAATZDJ-UHFFFAOYSA-N
• 유전자 정보: human ... CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779), CACNA2D1(781), NR3C2(4306)

설명

일반 설명

Felodipine is a dihydropyridine derivative. It has diuretic properties. Felodipine has high vascular selectivity. It is used to treat hypertension. Felodipine regulates chronic stable angina.

생화학적/생리학적 작용

L-type calcium channel blocker

특징 및 장점

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• 픽토그램: GHS08,GHS07,GHS09
• 신호어: Warning
• 유해 및 위험 성명서: H302,H361d,H373,H410
• 예방조치 성명서: P202 - P260 - P264 - P273 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2 Inhalation
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves