G2785

Glycitein

≥97% (HPLC)

• 동의어(들): 4′,7-Dihydroxy-6-methoxyisoflavone, Glycetein
• 실험식(Hill 표기법): C₁₆H₁₂O₅
• CAS Number: 40957-83-3
• Molecular Weight: 284.26
• MDL number: MFCD00016679
• UNSPSC 코드: 41106305
• PubChem Substance ID: 329799906
• NACRES: NA.51

속성

• 생물학적 소스: synthetic (organic)
• Quality Level: 100
• 분석: ≥97% (HPLC)
• 양식: powder
• solubility: DMF: 1 mg/mL, clear, colorless to faintly yellow
• 저장 온도: −20°C
• SMILES string: COc1cc2C(=O)C(=COc2cc1O)c3ccc(O)cc3
• InChI: 1S/C16H12O5/c1-20-15-6-11-14(7-13(15)18)21-8-12(16(11)19)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3
• InChI key: DXYUAIFZCFRPTH-UHFFFAOYSA-N

설명

애플리케이션

Glycitein has been used as standard for the analysis of soy isoflavones and metabolites in urine. It has also been used to bind to recombinant estrogen and progesterone receptors to know the relative binding affinity (RBA) for detection of potential endocrine disruptors.

생화학적/생리학적 작용

Glycitein is a soybean (yellow cultivar) isoflavonoid; its natural glycosides are synergistic with genistein in inducing specific gene expression. Glycitein may be used to study anti-oxidation processes at the level of gene transcription where it increases the binding of transcription factors [nuclear factor-E2-related factor 2 (Nrf2) and c-Jun] to the antioxidant response element (ARE) on HO-1 and NQO1 promoters. Glycitein may be used in combination with other isoflavonoids such as genistein and daidzein to study apoptosis.

Glycitein possesses weak estrogenic activity than other soy isoflavones.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)