I2411

Isocitrate Dehydrogenase 1 (NADP+) human

recombinant, expressed in Sf9 cells, ≥90% (SDS-PAGE)

• 동의어(들): IDH1, Isocitrate Dehydrogenase Cytoplasmic
• CAS Number: 9028-48-2
• EC 번호: 1.1.1.42 (BRENDA, IUBMB)
• UNSPSC 코드: 12352204
• NACRES: NA.54

속성

• 재조합: expressed in Sf9 cells
• Quality Level: 200
• 분석: ≥90% (SDS-PAGE)
• 양식: buffered aqueous glycerol solution
• 분자량: 47.6 kDa
• 농도: ≥0.30 mg/mL protein (Bradford)
• NCBI 수납 번호: NM_005896
• 관련 질환(들): cancer (lung)
• 배송 상태: dry ice
• 저장 온도: −70°C

설명

일반 설명

Human Isocitrate Dehydrogenase (IDH1), also known as oxalosuccinate decarboxylase, full length [amino acids 1-414 (end)] with C-terminal FLAG-tag, expressed in Sf9 cells via a baculovirus expression system.

애플리케이션

Human Isocitrate Dehydrogenase (IDH1) is useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. It may be useful as a biomarker for diagnosis and prognosis prediction of non-small cell lung cancer .

생화학적/생리학적 작용

Human Isocitrate Dehydrogenase (IDH1), also known as oxalosuccinate decarboxylase, is a full length amino acid with a C-terminal FLAG-tag and is expressed in Sf9 cells via a baculovirus expression system. IDH1 expression has been correlated with poor survival of non-small cell lung cancer. IDH1 promotes tumor growth .

물리적 형태

Solution in 45 mM Tris-HCl, 124 mM NaCl, 2.4 mM KCl, 90 μg/ml FLAG peptide, 3 mM DTT, and 10% glycerol at pH 8.0.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable