추천 제품
Product Name
Insulin-like Growth Factor-II human, IGF-II, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
생물학적 소스
human
Quality Level
재조합
expressed in E. coli
분석
≥98% (SDS-PAGE and HPLC)
양식
lyophilized powder
효능
≤2.0 ng/mL ED50
품질
endotoxin tested
분자량
7.5 kDa
포장
pkg of 5X50 μg
pkg of 50 μg
기술
cell culture | mammalian: suitable
불순물
≤0.1 EU/μg
UniProt 수납 번호
저장 온도
−20°C
유전자 정보
human ... IGF2(3481)
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생화학적/생리학적 작용
IGF-II, also known as multiplication stimulating activity (MSA), shows virtually identical bioactivities as IGF-I. IGF-II binds to the IGF-II receptor, IGF-I receptor, and weakly to the insulin receptor (IR). All IGF-II bioactivities in adult tissues are generally attributed to its interaction with IGF-I receptor. However, during embryogenesis the roles of both IGF-II receptor and IR may be significant in promoting normal growth.
Insulin-like growth factor II (IGF-II) also known as multiplication stimulating activity (MSA), shows virtually identical bioactivities as IGF-I. Expression of IGF-II is highest in fetal tissues, where it is believed to play a major role in overall growth and development. After birth IGF-II expression decreases to much lower levels in a variety of tissues. IGF-II is produced also in several tumors. IGF-II binds to IGF-II receptor (IGF-IIR), to IGF-IR and weakly to the insulin receptor (IR). All IGF-II bioactivities in adult tissues are generally attributed to its interaction with IGF-IR. However, during embryogenesis the roles of both IGF-IIR and IR may be significant in promoting normal growth.
물리적 형태
Lyophilized from a 0.2 μm filtered solution with no additives.
분석 메모
The biological activity is measured by a cell proliferation assay using mouse FDC-P1
관련 제품
제품 번호
설명
가격
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
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