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Merck
모든 사진(1)

주요 문서

I2526

Sigma-Aldrich

Insulin-like Growth Factor-II human

≥98% (SDS-PAGE and HPLC), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

동의어(들):

IGF-II

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About This Item

MDL number:
UNSPSC 코드:
12352202
NACRES:
NA.77

Product Name

Insulin-like Growth Factor-II human, IGF-II, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

생물학적 소스

human

Quality Level

재조합

expressed in E. coli

분석

≥98% (SDS-PAGE and HPLC)

양식

lyophilized powder

효능

≤2.0 ng/mL ED50

품질

endotoxin tested

분자량

7.5 kDa

포장

pkg of 5X50 μg
pkg of 50 μg

기술

cell culture | mammalian: suitable

불순물

≤0.1 EU/μg

UniProt 수납 번호

저장 온도

−20°C

유전자 정보

human ... IGF2(3481)

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생화학적/생리학적 작용

IGF-II, also known as multiplication stimulating activity (MSA), shows virtually identical bioactivities as IGF-I. IGF-II binds to the IGF-II receptor, IGF-I receptor, and weakly to the insulin receptor (IR). All IGF-II bioactivities in adult tissues are generally attributed to its interaction with IGF-I receptor. However, during embryogenesis the roles of both IGF-II receptor and IR may be significant in promoting normal growth.
Insulin-like growth factor II (IGF-II) also known as multiplication stimulating activity (MSA), shows virtually identical bioactivities as IGF-I. Expression of IGF-II is highest in fetal tissues, where it is believed to play a major role in overall growth and development. After birth IGF-II expression decreases to much lower levels in a variety of tissues. IGF-II is produced also in several tumors. IGF-II binds to IGF-II receptor (IGF-IIR), to IGF-IR and weakly to the insulin receptor (IR). All IGF-II bioactivities in adult tissues are generally attributed to its interaction with IGF-IR. However, during embryogenesis the roles of both IGF-IIR and IR may be significant in promoting normal growth.

물리적 형태

Lyophilized from a 0.2 μm filtered solution with no additives.

분석 메모

The biological activity is measured by a cell proliferation assay using mouse FDC-P1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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