I9659

Monoclonal Anti-Insulin-like Growth Factor-II antibody produced in mouse

clone 75014, purified immunoglobulin, lyophilized powder

• 동의어(들): Anti-IGF2, Anti-INSIGF
• MDL number: MFCD00162567
• UNSPSC 코드: 51111800
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 75014, monoclonal
• 양식: lyophilized powder
• 종 반응성: human
• 기술: western blot: 1-2 μg/mL
• 동형: IgG2a
• UniProt 수납 번호: P01344
• 저장 온도: −20°C
• 유전자 정보: human ... IGF2(3481)

설명

면역원

purified, E. coli-derived recombinant human insulin-like growth factor-II.

생화학적/생리학적 작용

Insulin-like growth factors -I and -II are important regulators of signaling that mediates growth and metabolism in cells. Insulin-like growth factor -II (IGF-II) is widely expressed during embryonic stages and regulates the placental development. IGF-II acts via specific receptor, IGF-IIR, the binding does not result in signal transduction, but is a mechanism to restrict the bioavailability of IGF-II. The effects of IGF-II signaling are important in growth of blood vessels (angiogenesis) gene transcription, proliferation and transformation.

물리적 형태

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

안전성 정보

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)