I9784

Monoclonal Anti-Insulin-like Growth Factor-II antibody produced in mouse

clone 75015, purified immunoglobulin, lyophilized powder

• 동의어(들): Anti-IGF2, Anti-INSIGF
• MDL number: MFCD00162567
• UNSPSC 코드: 51111800
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 75015, monoclonal
• 양식: lyophilized powder
• 종 반응성: human
• 기술: neutralization: suitable
• 동형: IgG1
• UniProt 수납 번호: P01344
• 저장 온도: −20°C
• 유전자 정보: human ... IGF2(3481)

설명

면역원

purified, E. coli-derived recombinant human insulin-like growth factor-II.

생화학적/생리학적 작용

Insulin-like growth factors -I and -II are important regulators of signaling that mediates growth and metabolism in cells. Insulin-like growth factor -II (IGF-II) is widely expressed during embryonic stages and regulates the placental development. IGF-II acts via specific receptor, IGF-IIR, the binding does not result in signal transduction, but is a mechanism to restrict the bioavailability of IGF-II. The effects of IGF-II signaling are important in growth of blood vessels (angiogenesis) gene transcription, proliferation and transformation.

물리적 형태

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)