L1026

Lidocaine

analytical standard

• 동의어(들): 2-Diethylamino-N-(2,6-dimethylphenyl)acetamide, Lignocaine, Xylocaine
• 실험식(Hill 표기법): C₁₄H₂₂N₂O
• CAS Number: 137-58-6
• Molecular Weight: 234.34
• EC Number: 205-302-8
• MDL number: MFCD00026733
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24896272
• NACRES: NA.77

속성

• Grade: analytical standard
• Quality Level: 200
• 양식: solid
• 포장: vial of 200 mg
• 기술: HPLC: suitable; gas chromatography (GC): suitable
• 불순물: ≤0.5% Total Organic Impurities (Lidocaine related compound H ≤0.10%; ; ; 2,6-Dimethylaniline ≤0.01%; ; ; Any unspecified impurity ≤0.10%; ; ; Total impurities ≤0.5%)
• 응용 분야: forensics and toxicology; pharmaceutical (small molecule)
• SMILES string: CCN(CC)CC(=O)Nc1c(C)cccc1C
• InChI: 1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)
• InChI key: NNJVILVZKWQKPM-UHFFFAOYSA-N
• 유전자 정보: human ... CYP1A2(1544), SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335) ; rat ... Scnn1a(25122)

설명

일반 설명

Lidocaine is an amide anesthetic, which is used to treat ventricular arrhythmias. It lowers cardiac automaticity and myocardial conduction. Lidocaine inhibits the generation and conduction of nerve impulses. It has an anticonvulsant effect.

애플리케이션

Lidocaine has been used to examine its effects in inhibiting lymph flow and protection against envenomation. It has also been used to assess its efficacy as an anti-tussive agent.

생화학적/생리학적 작용

Na⁺ channel blocker; class IB antiarrhythmic that is rapidly absorbed after parenteral administration.

Na⁺ channel blocker; class IB antiarrhythmic.

포장

Supplied in amber screw-cap vials

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Faceshields, Gloves