M1434

2-Methylthioadenosine 5′-monophosphate triethylammonium salt hydrate

solid, ≥98% (HPLC)

• 동의어(들): 2-MeSAMP, 2-Methylthio-AMP triethylammonium salt hydrate
• 실험식(Hill 표기법): C₁₁H₁₆N₅O₇PS · xC₆H₁₅N × yH₂O
• CAS Number: 22140-20-1
• Molecular Weight: 393.31 (anhydrous free acid basis)
• UNSPSC 코드: 41106305
• eCl@ss: 32160414
• PubChem Substance ID: 24896647
• NACRES: NA.51

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: solid
• 저장 조건: desiccated
• 색상: white
• solubility: H₂O: 20 mg/mL, clear, colorless
• 저장 온도: −20°C
• SMILES string: O.CCN(CC)CC.CSc1nc(N)c2ncn([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)c2n1
• InChI: 1S/C11H16N5O7PS.C6H15N.H2O/c1-25-11-14-8(12)5-9(15-11)16(3-13-5)10-7(18)6(17)4(23-10)2-22-24(19,20)21;1-4-7(5-2)6-3;/h3-4,6-7,10,17-18H,2H2,1H3,(H2,12,14,15)(H2,19,20,21);4-6H2,1-3H3;1H2/t4-,6-,7-,10-;;/m1../s1
• InChI key: YQMUWWZKFZERBT-IDIVVRGQSA-N

설명

애플리케이션

2-Methylthioadenosine 5′-monophosphate triethylammonium salt hydrate has been used:

• as a P2Y₁₂ inhibitor to study its effects on stimulation of endocytosis in high-density lipoprotein (HDL).
• as a P2Y₁₂ inhibitor to study its effects on platelet recruitment in whole human blood.

생화학적/생리학적 작용

2-Methylthioadenosine5′-monophosphate triethylammonium salt (2-MeSAMP) is an adenosine-based P2Y₁₂ antagonist and ADP-dependent platelet aggregation inhibitory agent.(1) It has a potential to inhibit platelet activation throughP2Y₁₂/G(i)-dependent mechanism.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)