M5793

3-Morpholinosydnonimine hydrochloride

(consistent with structure, NMR)

• 동의어(들): 3-(4-Morpholinyl)sydnone imine hydrochloride, Linsidomine hydrochloride, SIN-1 hydrochloride
• 실험식(Hill 표기법): C₆H₁₀N₄O₂ · HCl
• CAS Number: 16142-27-1
• Molecular Weight: 206.63
• MDL number: MFCD00214332
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24897048
• NACRES: NA.77

속성

• Quality Level: 200
• 저장 온도: −20°C
• SMILES string: Cl[H].[NH-]c1c[n+](no1)N2CCOCC2
• InChI: 1S/C6H10N4O2.ClH/c7-6-5-10(8-12-6)9-1-3-11-4-2-9;/h5,7H,1-4H2;1H
• InChI key: NCGICGYLBXGBGN-UHFFFAOYSA-N

설명

애플리케이션

3-Morpholinosydnonimine hydrochloride has been used:

• as a peroxynitrite donor standard to study the accumulation of peroxynitrite in Arabidopsis thaliana
• to study its effects on nitrosative stress in human brain vascular pericytes and human embryonic kidney cells
• as a ROS to study its effects on mouse embryonic fibroblasts

생화학적/생리학적 작용

3-Morpholinosydnonimine participates in the inhibition of cysteine proteases.

Liberates nitric oxide (NO) spontaneously when in solution, activating guanylyl cyclase and causing an increase in cyclic-GMP. This product is a vasodilator and inhibits platelet aggregation. Using molecular oxygen, it generates both superoxide anion and nitric oxide that spontaneously form peroxynitrite.

Liberates nitric oxide (NO) spontaneously when in solution, activating guanylyl cyclase and causing an increase in cyclic-GMP; vasodilator.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)