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M8386

α,β-Methyleneadenosine 5′-diphosphate sodium salt

Name: α,β-Methyleneadenosine 5′-diphosphate sodium salt
Brand: SIGMA

CD73 inhibitor

동의어(들):

AMP-CP

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About This Item

실험식(Hill 표기법):

C₁₁H₁₇N₅O₉P₂

CAS Number:

104835-70-3

Molecular Weight:

425.23

MDL number:

MFCD00070019

UNSPSC 코드:

41106305

PubChem Substance ID:

24897249

NACRES:

NA.51

추천 제품

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Sigma-Aldrich

M3763

Adenosine 5′-(α,β-methylene)diphosphate

Sigma-Aldrich

A2383

Adenosine 5′-triphosphate disodium salt hydrate

Sigma-Aldrich

L0288

Lipid Mixture 1, Chemically Defined

Sigma-Aldrich

A265

ARL 67156 trisodium salt hydrate

Sigma-Aldrich

A9251

Adenosine

Sigma-Aldrich

A2754

Adenosine 5′-diphosphate sodium salt

Sigma-Aldrich

M6517

α,β-Methyleneadenosine 5′-triphosphate lithium salt

Sigma-Aldrich

M7510

β,γ-Methyleneadenosine 5′-triphosphate disodium salt

Sigma-Aldrich

L5146

Lipid Mixture (1000×)

Sigma-Aldrich

T6397

3,3′,5-Triiodo-L-thyronine sodium salt

생물학적 소스

synthetic (organic)

Quality Level

200

분석

≥98% (HPLC)

양식

powder

solubility

water: 50 mg/mL, clear to slightly hazy, colorless

저장 온도

−20°C

SMILES string

[Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)CP(O)(O)=O)C(O)C3O

InChI

1S/C11H17N5O9P2.Na.H/c12-9-6-10(14-2-13-9)16(3-15-6)11-8(18)7(17)5(25-11)1-24-27(22,23)4-26(19,20)21;;/h2-3,5,7-8,11,17-18H,1,4H2,(H,22,23)(H2,12,13,14)(H2,19,20,21);;

InChI key

HEBWZOPLDYDXPJ-UHFFFAOYSA-N

애플리케이션

α,β-Methyleneadenosine 5′-diphosphate sodium salt has been used as an ectonucleotidase/CD73 inhibitor to characterize the mode of adenosine production and as an inhibitor for in vitro studies.

생화학적/생리학적 작용

α, β-Methyleneadenosine 5′-diphosphate (AMP-CP) is an ADP analog that as an ability to inhibit ectonucleotidase/ CD73 inhibitor and is used to study adenosinergic signaling regulation via CD73/ecto-5′-nucleotidase.