N3279

Monoclonal Anti-Nerve Growth Factor-β antibody produced in mouse

clone 25623, purified immunoglobulin, lyophilized powder

• 동의어(들): Anti-NGF-β
• MDL number: MFCD00282385
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 200
• 결합: unconjugated
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 25623, monoclonal
• 양식: lyophilized powder
• 종 반응성: human, rat, mouse
• 기술: capture ELISA: 2-8 μg/mL (detection antibody at 0.1-0.4 μg/ml); neutralization: 0.1-0.4 μg/mL
• 불순물: endotoxin, tested
• 동형: IgG1
• UniProt 수납 번호: P01138
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... NGF(4803) ; mouse ... Ngf(18049)

설명

면역원

recombinant human NGF-β.

생화학적/생리학적 작용

Nerve Growth factor (NGF) is a growth factor that is essential for the development and maintenance of the nervous system. NGF is composed of three non-covalently linked α, β and γ subunits. The β subunit is responsible for the biological functions of NGF. Nerve growth factor (NGF) binds to either to NGF receptor (NGFR) or the Trk receptor and can elicit biological responses through each of the receptors independently. NGF is important in the survival and differentiation of neurons and neural crest-derived cells during embryonic and early postnatal development and maintenance of peripheral neurons. NGF is also implicated in inflammation and allergic reactions.

물리적 형태

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

제조 메모

Purified using Protein G.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)