O6881

Oxypurinol

≥98% (HPLC)

• 실험식(Hill 표기법): C₅H₄N₄O₂
• CAS Number: 2465-59-0
• Molecular Weight: 152.11
• EC Number: 219-570-9
• MDL number: MFCD00056934
• UNSPSC 코드: 41106305
• PubChem Substance ID: 24898041
• NACRES: NA.51

속성

• Quality Level: 200
• 분석: ≥98% (HPLC)
• 양식: powder
• solubility: 1 M NaOH: 49.00-51.00 mg/mL, clear to slightly hazy, colorless to yellow (heated NaOH)
• SMILES string: O=C1NC(=O)c2cn[nH]c2N1
• InChI: 1S/C5H4N4O2/c10-4-2-1-6-9-3(2)7-5(11)8-4/h1H,(H3,6,7,8,9,10,11)
• InChI key: HXNFUBHNUDHIGC-UHFFFAOYSA-N

설명

애플리케이션

Oxypurinol has been used as a xanthine oxidase inhibitor, to evaluate its effects on hepatocellular carcinoma cell proliferation. It has also been used as a xanthine inhibitor to elucidate its contribution in the induction of hpv16 late gene expression.

Oxypurinol, an allopurinol metabolite, is used as an inhibitor to study the specificity and kinetics of of xanthine oxidase(s). Oxypurinol is also used as an anti-inflammatory agent via inhibition of xanthine oxidase.

생화학적/생리학적 작용

An allopurinol metabolite.

Oxypurinol has the ability to stimulate osteoblast differentiation and enhance the formation of bone. It is used to treat gout and hyperuricemia. Oxypurinol is considered as a strong antioxidant. It can prevent the actions of xanthine oxidase (XO) in osteoblasts.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves