P152

S(–)-Pindolol

solid

• 실험식(Hill 표기법): C₁₄H₂₀N₂O₂
• CAS Number: 26328-11-0
• Molecular Weight: 248.32
• MDL number: MFCD00153863
• UNSPSC 코드: 12352202
• PubChem Substance ID: 24278026

속성

• 양식: solid
• 광학 활성: [α]23/D −4.38°, c = 1% in methanol(lit.)
• 색상: white
• solubility: 0.1 M NaOH: 0.2 mg/mL; methanol: 18 mg/mL; 0.1 M HCl: 20 mg/mL; 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 3.4 mg/mL; H₂O: insoluble
• 주관자: Novartis
• SMILES string: CC(C)NC[C@H](O)COc1cccc2[nH]ccc12
• InChI: 1S/C14H20N2O2/c1-10(2)16-8-11(17)9-18-14-5-3-4-13-12(14)6-7-15-13/h3-7,10-11,15-17H,8-9H2,1-2H3/t11-/m0/s1
• InChI key: JZQKKSLKJUAGIC-NSHDSACASA-N
• 유전자 정보: human ... ADRB1(153), HTR1A(3350), HTR1B(3351)

설명

생화학적/생리학적 작용

β₁-adrenoceptor antagonist; putative 5-HT_1A serotonin receptor agonist; vasodilator. Active enantiomer of pindolol.

특징 및 장점

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)