PZ0332

ISOX-INACT

≥98% (HPLC)

• 동의어(들): 4-(2-(5-(3,5-Dimethylisoxazol-4-yl)-2-(4-methoxyphenethyl)-4,6-dimethyl-1Hbenzo[d]imidazol-1-yl)ethyl)morpholine
• 실험식(Hill 표기법): C₂₉H₃₆N₄O₃
• CAS Number: 1962928-29-5
• Molecular Weight: 488.62
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329823843
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 5 mg/mL, clear (warmed)
• 저장 온도: room temp
• SMILES string: CC1=NOC(C)=C1C2=C(C)C(N=C(CCC3=CC=C(OC)C=C3)N4CCN5CCOCC5)=C4C=C2C
• InChI: 1S/C29H36N4O3/c1-19-18-25-29(20(2)27(19)28-21(3)31-36-22(28)4)30-26(11-8-23-6-9-24(34-5)10-7-23)33(25)13-12-32-14-16-35-17-15-32/h6-7,9-10,18H,8,11-17H2,1-5H3
• InChI key: FTOHXUPHICJSCR-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

CBP BRD (CREB binding protein bromodomain) inhibition serves as an effective therapeutic target for Parkinson′s disease. The inhibition is followed by negative regulation of a number of macrophage inflammatory genes. It also downregulates G-protein signaling 4 mRNA.

ISOX-INACT is an inactive control probe for the highly-selective inhibitor of the bromodomain of CREB binding protein (CBP BRD) PF-CBP1.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable