SAB4200175

Anti-Atg101 antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody

• 동의어(들): Anti-Atg13-interacting protein, Anti-C12orf44, Anti-autophagy-related protein 101, Anti-chromosome 12 open reading frame 44
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 분자량: ~30 kDa
• 종 반응성: human
• 농도: ~1.0 mg/mL
• 기술: western blot: 0.25-0.5 μg/mL using whole extracts of HEK-293T cells over expressing human Atg101
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... C12orf44(60673)

설명

일반 설명

Autophagy101 (Atg101) is located on the human chromosome at 12q13.13.

애플리케이션

Anti-Atg101 antibody has been used in

• immunoblotting
• immunofluorescence
• immunopurification

생화학적/생리학적 작용

Autophagy101 (Atg101) is a mammalian Autophagy13 (Atg13) binding protein essential for autophagy. Atg13 forms a stable complex with ULK1 (Serine/threonine-protein kinase ULK1) and FIP200 (FAK family kinase-interacting protein of 200 kDa). Atg101 associates with the ULK1-Atg13- FIP200 complex through direct interaction with Atg13. Mammalian target of rapamycin (mTOR) interacts with the ULK1-Atg13-FIP200 complex in a nutrient dependent manner, suggesting that mTOR regulates autophagy through this complex.

물리적 형태

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable