SCP0002

Acetyl-Amyloid β 25-35

• 실험식(Hill 표기법): C₄₇H₈₃N₁₃O₁₅S₁
• Molecular Weight: 1102.31
• UNSPSC 코드: 12352202
• NACRES: NA.32

속성

• 분석: ≥95% (HPLC)
• 양식: lyophilized
• 구성: Peptide Content, ≥70%
• 저장 조건: protect from light
• UniProt 수납 번호: P05067
• 저장 온도: −20°C
• 유전자 정보: human ... APP(351)

설명

Amino Acid Sequence

Ac-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met

일반 설명

Amyloid-β (Aβ) peptides are a major component of the senile plaques characteristic of the Alzheimer brain. It is a type- I transmembrane protein. The amyloid β precursor protein is cleaved to amyloid peptides 36-43 amino acids in length. Aβ (25-35) represents the region that aggregates during plaque formation and is a functional domain implicated in both neurotrophic and neurotoxic effects. The gene encoding amyloid-β is localized on human chromosome 21. Acetylation may improve stability in in vitro and in vivo assays.

애플리케이션

Acetyl-Amyloid β 25-35 has been used to prepare rat models with Alzheimer′s disease.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable