SML0296

Pyroxamide

≥97% (HPLC)

• 동의어(들): N1-Hydroxy-N8-3-pyridinyl-octanediamide
• 실험식(Hill 표기법): C₁₃H₁₉N₃O₃
• CAS Number: 382180-17-8
• Molecular Weight: 265.31
• MDL number: MFCD13194970
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329825303
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥97% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 10 mg/mL (clear solution)
• 저장 온도: −20°C
• SMILES string: ONC(=O)CCCCCCC(=O)Nc1cccnc1
• InChI: 1S/C13H19N3O3/c17-12(15-11-6-5-9-14-10-11)7-3-1-2-4-8-13(18)16-19/h5-6,9-10,19H,1-4,7-8H2,(H,15,17)(H,16,18)
• InChI key: PTJGLFIIZFVFJV-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

Pyroxamide is an inhibitor of HDAC1 (IC₅₀ = 100 nM). Pyroxamide induces apoptosis and cell cycle arrest in leukemia, bladder and prostate cancer cell lines.

Pyroxamide is an inhibitor of HDAC1.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable