T7165

Tyrphostin 23

≥98%

• 동의어(들): (3,4-Dihydroxybenzylidene)malononitrile, RG-50810
• 실험식(Hill 표기법): C₁₀H₆N₂O₂
• CAS Number: 118409-57-7
• Molecular Weight: 186.17
• MDL number: MFCD00133899
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24278041
• NACRES: NA.77

속성

• 생물학적 소스: synthetic (organic)
• Quality Level: 100
• 분석: ≥98%
• 양식: powder
• 효능: 35 μM IC₅₀
• solubility: DMSO: soluble 50 mg/mL, clear, yellow to brownish-yellow
• 저장 온도: 2-8°C
• SMILES string: Oc1ccc(cc1O)\C=C(\C#N)C#N
• InChI: 1S/C10H6N2O2/c11-5-8(6-12)3-7-1-2-9(13)10(14)4-7/h1-4,13-14H
• InChI key: VTJXFTPMFYAJJU-UHFFFAOYSA-N
• 유전자 정보: human ... CDK2(1017)

설명

애플리케이션

Tyrphostin 23 can be used as a tyrosine kinase inhibitor for studying rat ghrelin-induced MAPK stimulation in GH3 cells. Tyrphostin 23 has also been used to analyze its effects on secretoneurin (SN)-induced chemotaxis of neutrophils.

생화학적/생리학적 작용

Tyrphostin 23 is a small molecule inhibitor of epidermal growth factor (EGF) receptor kinase function. This molecule associates with the substrate subsite of the protein tyrosine kinase (PTK) domain,.

특징 및 장점

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안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)