T7205

Tegafur

≥98% (HPLC), powder

• 동의어(들): 5-Fluoro-1-(tetrahydro-2-furyl)uracil, Ftorafur, Tegafur
• 실험식(Hill 표기법): C₈H₉FN₂O₃
• CAS Number: 17902-23-7
• Molecular Weight: 200.17
• EC Number: 241-846-2
• MDL number: MFCD00012351
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329826861
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to off-white
• mp: 171-173 °C (lit.)
• solubility: DMSO: >50 mg/mL
• 저장 온도: room temp
• SMILES string: FC1=CN(C2CCCO2)C(=O)NC1=O
• InChI: 1S/C8H9FN2O3/c9-5-4-11(6-2-1-3-14-6)8(13)10-7(5)12/h4,6H,1-3H2,(H,10,12,13)
• InChI key: WFWLQNSHRPWKFK-UHFFFAOYSA-N

설명

애플리케이션

Tegafur has been used as an internal standard for the analysis of 5′DFCR (5′deoxyfluorocytidine) and 5′DFUR (5′deoxyfluorouridine) using HPLC techniques. Tegafur has also been used as an internal standard for the chromatographic assay of azidothymidine (AZT).

생화학적/생리학적 작용

Tegafur is a pro-drug of 5-fluorouracil, an antimetabolite used as an antineoplastic agent. It has been used as adjuvant chemotherapy for curatively resected colorectal cancer therapy.

제조 메모

Tegafur is soluble in DMSO at a concentration that is greater than 50 mg/ml.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H301 + H311 + H331
• 예방조치 성명서: P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable