T7697

I-OMe-Tyrphostin AG 538

solid

• 동의어(들): α-Cyano-(3-methoxy-4-hydroxy-5-iodocinnamoyl)-(3′,4′-dihydroxyphenyl)ketone, I-OMe-AG 538
• 실험식(Hill 표기법): C₁₇H₁₂INO₅
• CAS Number: 1094048-77-7
• Molecular Weight: 437.19
• MDL number: MFCD03453582
• UNSPSC 코드: 12352203
• PubChem Substance ID: 24278758
• NACRES: NA.77

속성

• 양식: solid
• Quality Level: 100
• solubility: DMSO: 50 mg/mL
• 저장 온도: −20°C
• SMILES string: COc1cc(cc(I)c1O)\C=C(/C#N)C(=O)c2ccc(O)c(O)c2
• InChI: 1S/C17H12INO5/c1-24-15-6-9(5-12(18)17(15)23)4-11(8-19)16(22)10-2-3-13(20)14(21)7-10/h2-7,20-21,23H,1H3/b11-4+
• InChI key: HSRMHXWCTRFVHK-NYYWCZLTSA-N
• 유전자 정보: human ... IGF1(3479), IGF1R(3480)

설명

애플리케이션

I-OMe-Tyrphostin AG 538 has been used as a cell signaling inhibitor in PC-1 cell lines. It has also been used in high throughput screening assays for IGF1R inhibitors.

생화학적/생리학적 작용

Insulin growth factor 1 (IGF-1) receptor protein tyrosine kinase inhibitor.

특징 및 장점

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제조 메모

I-OMe-Tyrphostin AG 538 is soluble in DMSO at 50 mg/ml.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)