324450

(S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine

96%

• Empirical Formula (Hill Notation): C₉H₁₈N₂
• CAS Number: 51207-66-0
• Molecular Weight: 154.25
• MDL number: MFCD00013441
• UNSPSC Code: 12352005
• PubChem Substance ID: 24859441
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 96%
• optical activity: [α]19/D +7.0°, c = 2.4 in ethanol
• refractive index: n20/D 1.4871 (lit.)
• bp: 99-101 °C/2 mmHg (lit.)
• density: 0.946 g/mL at 25 °C (lit.)
• SMILES string: C1CCN(C1)C[C@@H]2CCCN2
• InChI: 1S/C9H18N2/c1-2-7-11(6-1)8-9-4-3-5-10-9/h9-10H,1-8H2/t9-/m0/s1
• InChI key: YLBWRMSQRFEIEB-VIFPVBQESA-N

Description

Application

(S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine can be used as an organocatalyst in the asymmetric synthesis of different optically active organic building blocks via Aldol condensation and Mannich reactions . It is also used as a catalyst to prepare enantioselective Michael adducts by reacting alkylidene malonates with unactivated ketones.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 190.4 °F - closed cup
• flash_point_c: 88 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter