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QBD10313

Sigma-Aldrich

Fmoc-N-amido-dPEG®24-acid

Synonym(s):

Polyethylene glycol

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About This Item

Empirical Formula (Hill Notation):
C66H113NO28
Molecular Weight:
1368.59
MDL number:
MFCD11041159
UNSPSC Code:
12352106
PubChem Substance ID:
329823913
NACRES:
NA.22
Pricing and availability is not currently available.

assay

>90%

form

solid or viscous liquid

reaction suitability

reaction type: Pegylations
reagent type: cross-linking reagent

functional group

Fmoc

polymer architecture

shape: linear
functionality: heterobifunctional

shipped in

ambient

storage temp.

−20°C

SMILES string

OC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)=O

InChI key

NFOMZHGRFWXDGH-UHFFFAOYSA-N

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This Item
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Fmoc-N-amido-dPEG®24-acid

QBD10313

Fmoc-N-amido-dPEG®24-acid

Fmoc-N-amido-dPEG®12-acid

QBD10283

Fmoc-N-amido-dPEG®12-acid

Fmoc-N-amido-dPEG®4-acid

QBD10213

Fmoc-N-amido-dPEG®4-acid

Fmoc-N-amido-dPEG ®24-TFP ester

QBD11007

Fmoc-N-amido-dPEG ®24-TFP ester

polymer architecture

shape: linear
functionality: heterobifunctional

polymer architecture

shape: linear
functionality: heterobifunctional

polymer architecture

shape: linear
functionality: heterobifunctional

polymer architecture

shape: linear
functionality: heterobifunctional

assay

>90%

assay

>90%

assay

>90%

assay

>90%

functional group

Fmoc

functional group

Fmoc

functional group

Fmoc, amine, carboxylic acid

functional group

Fmoc

form

solid or viscous liquid

form

solid or viscous liquid

form

solid or viscous liquid

form

solid or viscous liquid

reaction suitability

reaction type: Pegylations, reagent type: cross-linking reagent

reaction suitability

reaction type: Pegylations, reagent type: cross-linking reagent

reaction suitability

reaction type: Pegylations, reagent type: cross-linking reagent

reaction suitability

reaction type: Pegylations, reagent type: cross-linking reagent

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Features and Benefits

Fmoc-N-amido-dPEG®24-acid is a novel Fmoc-protected amino acid containing a single molecular weight PEG (dPEG®) spacer arm. This reagent is used to introduce a hydrophilic, non-immunogenic spacer into a peptide (89 Å). Three different lengths of dPEG® allow precise control of spacing and hydrophilicity. Fmoc group can be removed, exposing the terminal amine, using piperidine as with standard peptide synthesis.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

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    Josef Dib et al.
    Journal of mass spectrometry : JMS, 50(2), 407-417 (2015-03-25)
    AdipoR agonists are small, orally active molecules capable of mimicking the protein adiponectin, which represents an adipokine with antidiabetic and antiatherogenic effects. Two adiponectin receptors were reported in the literature referred to as adipoR1 and adipoR2. Activation of these receptors

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