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I0879

Sigma-Aldrich

Inosine 5′-triphosphate trisodium salt

≥95%

Synonyme(s) :

ITP

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About This Item

Formule empirique (notation de Hill) :
C10H12Na3N4O14P3
CAS Number:
35908-31-7
Poids moléculaire :
574.11
Numéro MDL:
MFCD00084678
Code UNSPSC :
41106305
ID de substance PubChem :
24895910
Nomenclature NACRES :
NA.51
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Niveau de qualité

200

Essai

≥95%

Conditions d'expédition

dry ice

Température de stockage

−20°C

Chaîne SMILES 

[Na].OC1C(O)C(OC1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n2cnc3C(=O)N=CNc23

InChI

1S/C10H15N4O14P3.Na.H/c15-6-4(1-25-30(21,22)28-31(23,24)27-29(18,19)20)26-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;;/h2-4,6-7,10,15-16H,1H2,(H,21,22)(H,23,24)(H,11,12,17)(H2,18,19,20);;

Clé InChI

RIERCUPIZLBNFQ-UHFFFAOYSA-N

Informations sur le gène

human ... HRAS(3265)

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CL 316,243 hydrate ≥98% (HPLC), powder

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Altanserin hydrochloride hydrate ≥98% (HPLC), solid

A8106

Altanserin hydrochloride hydrate

form

powder

form

powder

form

powder

form

solid

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

room temp

storage temp.

2-8°C

storage condition

desiccated

storage condition

-

storage condition

-

storage condition

-

solubility

H2O: ≥15 mg/mL

solubility

H2O: ≥10 mg/mL

solubility

H2O: 10 mg/mL, clear

solubility

DMSO: >5 mg/mL, H2O: insoluble

Application

Inosine 5′-triphosphate (ITP) is used in studies on the impact of deamination of ATP and GTP by various enzymes and chemical processes. ITP may be used as a substrate to study the specificity and kinetics of nucleoside-5′-triphosphatase and ATPase. ITP is also used to study activation of various ATPases and GTPases.
Inosine 5′-triphosphate trisodium salt has been used to investigate its influence on the chromosome aberration rate, the mitotic rate, sister-chromatid exchange (SCE) frequency, the proportion of first (X1), second (X2) and third (X3) division metaphases of human peripheral lymphocytes.[1]

Actions biochimiques/physiologiques

Inosine 5′-triphosphate (ITP) has the ability to support the initiation of effector system. It can prevent guanosine 5′-triphosphate (GTP) hydrolysis, that is catalysed by transducin (TD). ITP can proficiently induce secretion in permeabilized cells than GTP.[2] Instead of GTP, ITP can be used for the initiation and the elongation steps of reovirus transcription.[3] ITP can also replace GTP in the activation of G-protein.[2]

Notes préparatoires

Prepared from Bacterial ATP

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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    Certificats d'analyse (COA)

    Lot/Batch Number
    SLCK1930
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    SLBM2892V

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