I3275

Interferon-γ from rat

≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

• Synonyme(s) : IFN-γ
• Numéro MDL: MFCD00283531
• Code UNSPSC : 12352202
• Nomenclature NACRES : NA.32

Propriétés

• Source biologique: rat
• Niveau de qualité: 200
• Produit recombinant: expressed in E. coli
• Essai: ≥97% (SDS-PAGE)
• Forme: lyophilized powder
• Poids mol.: 15.5 kDa
• Conditionnement: pkg of 0.1 mg
• Technique(s): cell culture | mammalian: suitable
• Impuretés: endotoxin, tested
• Couleur: white
• Numéro d'accès UniProt: P01581
• Température de stockage: −20°C
• Informations sur le gène: rat ... Ifng(25712)

Description

Application

Interferon-γ from rat has been used to study the effect of lipoxin A4 and 17(R)-resolvin D1 on lipopolysaccharide and interferon-γ-mediated tumor necrosis factor release in rat astrocyte culture. In rats, it has been used in the treatment of INS-1 cell culture to study the conversion factors which change the frequency of β-cell replication or apoptosis to rates of replication or apoptosis.

Actions biochimiques/physiologiques

Ifng (interferon-γ) plays an important role in innate and adaptive immune responses, and helps in defense against bacterial infections, dimorphic yeast and some viral infections. In rats, it is upregulated during ischemic injury in the embolic stroke. In cultured rat intestinal mucosa microvascular endothelial cells, ifng is responsible for inducing expression of interferon-α and interferon-β.

Caractéristiques et avantages

The biological activity is measured in an anti-viral assay using L-929 cells infected with EMC virus.

Forme physique

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 50 μg of bovine serum albumin per 1 μg of cytokine.

Informations sur la sécurité

• Code de la classe de stockage: 13 - Non Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)