C5490

C75

≥98% (HPLC), powder

• 동의어(들): 4-Methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid
• 실험식(Hill 표기법): C₁₄H₂₂O₄
• CAS Number: 218137-86-1
• Molecular Weight: 254.32
• MDL number: MFCD03426157
• UNSPSC 코드: 41121801
• PubChem Substance ID: 24892789
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 5 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: CCCCCCCCC1OC(=O)C(=C)C1C(O)=O
• InChI: 1S/C14H22O4/c1-3-4-5-6-7-8-9-11-12(13(15)16)10(2)14(17)18-11/h11-12H,2-9H2,1H3,(H,15,16)
• InChI key: VCWLZDVWHQVAJU-UHFFFAOYSA-N

설명

애플리케이션

C75 has been used:

• as a fatty acid synthase (FASN) inhibitor to test its ability in the direct inhibition of FASN to attenuate mammosphere formation as compared to metformin
• as a pharmacological inhibitor to inhibit fatty acid synthesis in glioma stem cells (GSCs)
• as FAS inhibitor in the pre-treatment of Chang cells to inhibit lipogenesis and reverse the senescence induced by hydrogen peroxide

생화학적/생리학적 작용

C75 helps to increase the cancer‐killing capability of ionizing radiation.

C75 is a novel, potent synthetic inhibitor of fatty acid synthase (FAS), which is used as a tool for studying fatty acid synthesis in metabolic disorders and cancer.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)