D7408

2′,5′-Dideoxyadenosine

≥95% (HPLC), solid

• 동의어(들): 2ʹ,5ʹ-dd-Ado, NSC 95943
• 실험식(Hill 표기법): C₁₀H₁₃N₅O₂
• CAS Number: 6698-26-6
• Molecular Weight: 235.24
• MDL number: MFCD00210904
• UNSPSC 코드: 41106305
• PubChem Substance ID: 24894132
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥95% (HPLC)
• 양식: solid
• 색상: white
• solubility: DMSO: soluble
• 저장 온도: −20°C
• SMILES string: C[C@H]1O[C@H](C[C@@H]1O)n2cnc3c(N)ncnc23
• InChI: 1S/C10H13N5O2/c1-5-6(16)2-7(17-5)15-4-14-8-9(11)12-3-13-10(8)15/h3-7,16H,2H2,1H3,(H2,11,12,13)/t5-,6+,7-/m1/s1
• InChI key: FFHPXOJTVQDVMO-DSYKOEDSSA-N
• 유전자 정보: rat ... Adcy2(81636)

설명

애플리케이션

2′,5′-Dideoxyadenosine has been used to elucidate the mechanism of diligustilide (DLG). It has also been used to inhibit adenylate cyclase (AC).

생화학적/생리학적 작용

Cell-permeable adenylyl cyclase inhibitor. IC₅₀ = 2.7 μM in detergent-dispersed rat brain preparations.

특징 및 장점

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Adenylyl cyclases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

재구성

Store at −20 °C after reconstitution.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)