H128

(R)(−)-α-Methylhistamine dihydrochloride

solid, ≥98% (HPLC)

• 동의어(들): (R)(−)-α-Methyl-1H-imidazole-4-ethanamine dihydrochloride
• 실험식(Hill 표기법): C₆H₁₁N₃ · 2HCl
• CAS Number: 75614-89-0
• Molecular Weight: 198.09
• MDL number: MFCD00083176
• UNSPSC 코드: 12352116
• PubChem Substance ID: 24277778
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: solid
• 광학 활성: [α]22/D −4°, c = 0.8 in H₂O(lit.)
• 저장 조건: desiccated
• 색상: white to off-white
• solubility: H₂O: soluble
• SMILES string: Cl.Cl.C[C@@H](N)Cc1c[nH]cn1
• InChI: 1S/C6H11N3.2ClH/c1-5(7)2-6-3-8-4-9-6;;/h3-5H,2,7H2,1H3,(H,8,9);2*1H/t5-;;/m1../s1
• InChI key: IZHCNQFUWDFPCW-ZJIMSODOSA-N
• 유전자 정보: human ... HRH3(11255)

설명

애플리케이션

(R)(−)-α-Methylhistamine dihydrochloride has been used as an agonist for the histamine H3 cell lines. It has also been used in the antagonist assay for the histamine H3 cell lines.

생화학적/생리학적 작용

(R)(−)-α-Methylhistamine dihydrochloride is a potent, selective H₃ histamine receptor agonist which crosses the blood-brain barrier. It can inhibit histamine synthesis and release.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves