I6784

Monoclonal Anti-Interleukin-2 antibody produced in mouse

clone 5334, purified immunoglobulin, lyophilized powder

• 동의어(들): Anti-IL2, Anti-Lymphokine, Anti-TCGF
• UNSPSC 코드: 51111800
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 5334, monoclonal
• 양식: lyophilized powder
• 종 반응성: human
• 기술: flow cytometry: 25 μg/mL; immunohistochemistry: 8-25 μg/mL; neutralization: suitable
• 동형: IgG1
• UniProt 수납 번호: P60568
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... IL2(3558)

설명

일반 설명

Interleukin-2 (IL-2) is a cytokine produced by activated T cells in response to antigen stimulation. IL-2 is important for proliferation of lymphocytes, natural killer cells and macrophages and in the differentiation of CD4⁺ cells into Th1 and Th2 effector cells. The effects of IL-2 are mediated by the signalling activated by its binding to IL-2 receptor (IL-2 R). IL-2 activates key signalling pathways such as MAPK, JAK/STAT as well as PI3K/Akt. Activation of these pathways modulates production of inflammatory cytokines, survival and progression through cell cycle
Monoclonal Anti-Interleukin-2 recognizes human Interleukin-2. It does not react with mouse IL-2.

면역원

purified, E. coli-derived recombinant human interleukin-2.

애플리케이션

Anti-interleukin-2 antibody may be used in immunohistochemistry at a working concentration of 8-25 μg/ml in human peripheral blood leukocytes. For flow cytometry a concentration of 25 μg/ml may be used. The antibody is suitable for IL-2 neutralization assays.

물리적 형태

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)