I8273

Anti-Interleukin-2 antibody produced in goat

IgG fraction of antiserum, lyophilized powder

• 동의어(들): Anti-IL-2
• MDL number: MFCD00675261
• UNSPSC 코드: 51111800
• NACRES: NA.46

속성

• 생물학적 소스: goat
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: IgG fraction of antiserum
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: lyophilized powder
• 종 반응성: human
• 기술: neutralization: suitable; western blot: 1 μg/mL
• UniProt 수납 번호: P60568
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... IL2(3558)

설명

일반 설명

Interleukin-2 (IL-2) is a cytokine produced by activated T cells in response to antigen stimulation. IL-2 is important for proliferation of lymphocytes, natural killer cells and macrophages and in the differentiation of CD4⁺ cells into Th1 and Th2 effector cells. The effects of IL-2 are mediated by the signalling activated by its binding to IL-2 receptor (IL-2 R). IL-2 activates key signalling pathways such as MAPK, JAK/STAT as well as PI3K/Akt. Activation of these pathways modulates production of inflammatory cytokines, survival and progression through cell cycle
Monoclonal Anti-Interleukin-2 recognizes human Interleukin-2. It also neutralizes recombinant, mouse IL-2, but requires 30-50 times the antibody concentration required to neutralize human IL-2.

특이성

The antibody neutralizes the biological activity of recombinant human IL-2.

면역원

recombinant human interleukin-2 expressed in Escherichia coli.

애플리케이션

Anti-interleukin-2 antibody is suitable for IL-2 neutralization assays.

물리적 형태

Lyophilized from a 0.2 μm filtered solution of phosphate buffered saline containing carbohydrates.

제조 메모

Purified using protein G.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)