I6909

Monoclonal Anti-Interleukin-2 antibody produced in mouse

clone 5355, purified immunoglobulin, lyophilized powder

• 동의어(들): Anti-IL2, Anti-Lymphokine, Anti-TCGF
• UNSPSC 코드: 51111800
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 5355, monoclonal
• 양식: lyophilized powder
• 종 반응성: human
• 기술: capture ELISA: 2-8 μg/mL; immunohistochemistry: 8-25 μg/mL
• 동형: IgG2a
• UniProt 수납 번호: P60568
• 저장 온도: −20°C
• 유전자 정보: human ... IL2(3558)

설명

면역원

purified, E. coli-derived recombinant human interleukin-2.

생화학적/생리학적 작용

Interleukin-2 (IL-2) is a cytokine produced by activated T cells in response to antigen stimulation. IL-2 is important for proliferation of lymphocytes, natural killer cells and macrophages and in the differentiation of CD4⁺ cells into Th1 and Th2 effector cells. The effects of IL-2 are mediated by the signaling activated by its binding to IL-2 receptor (IL-2 R). IL-2 activates key signaling pathways such as MAPK, JAK/STAT as well as PI3K/Akt. Activation of these pathways modulates production of inflammatory cytokines, survival and progression through cell cycle.

물리적 형태

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)